英文名稱 | N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ | N-Acetyl-γ-calicheamicin) |
---|---|
中文名稱 | N-乙酰-卡利奇霉素 |
CAS號 | 108212-76-6 |
分子式 | C57H76IN3O22S4 |
分子量 | 1410.39 |
外觀 | White to off-white powder |
儲存條件 | 4°C, sealed storage, away from moisture |
英文名稱 | N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ | N-Acetyl-γ-calicheamicin) |
---|---|
中文名稱 | N-乙酰-卡利奇霉素 |
CAS號 | 108212-76-6 |
分子式 | C57H76IN3O22S4 |
分子量 | 1410.39 |
外觀 | White to off-white powder |
儲存條件 | 4°C, sealed storage, away from moisture |
N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ), an enediyne anti-tumor antibiotic, is an ADC cytotoxin. N-Acetyl-Calicheamicin can induce DNA damage, and can be used in the synthesis of ADC.
PMID: 34155147 PMCID: PMC8237573 DOI: 10.1073/pnas.2107042118
Calicheamicin Antibody-Drug Conjugates with Improved Properties.
PMID: 33722856 DOI: 10.1158/1535-7163.MCT-20-0035