英文名稱 | CP-547632 | PAN-90806 | CP-632 | OSI-632 |
---|---|
中文名稱 | CP-547632 |
CAS號 | 252003-65-9 |
分子式 | C20H24BrF2N5O3S |
分子量 | 532.40 |
外觀 | White to light yellow powder |
儲存條件 | 4°C, stored under nitrogen |
英文名稱 | CP-547632 | PAN-90806 | CP-632 | OSI-632 |
---|---|
中文名稱 | CP-547632 |
CAS號 | 252003-65-9 |
分子式 | C20H24BrF2N5O3S |
分子量 | 532.40 |
外觀 | White to light yellow powder |
儲存條件 | 4°C, stored under nitrogen |
CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than for EGFR, PDGFRβ and related tyrosine kinases (TKs). PDGFRβ and related tyrosine kinases (TKs) CP-547632 has antitumour activity.