英文名稱 | WYE-132(WYE-125132) |
---|---|
中文名稱 | WYE-132(WYE-125132) |
CAS號 | 1144068-46-1 |
分子式 | C27H33N7O4 |
分子量 | 519.60 |
外觀 | White to gray powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | WYE-132(WYE-125132) |
---|---|
中文名稱 | WYE-132(WYE-125132) |
CAS號 | 1144068-46-1 |
分子式 | C27H33N7O4 |
分子量 | 519.60 |
外觀 | White to gray powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
WYE-125132 (also known as WYE 132) is a novel, highly potent, selective and ATP-competitive inhibitor of mTOR (mammalian target of rapamycin) with potential antitumor activity. It inhibits mTOR with an IC50 of 0.19 nM; It exhibits high selectivity for mTOR over PI3K and inhibits mTOR with an IC50 of 0.19 nM.