英文名稱 | Brivanib | BMS-540215 |
---|---|
中文名稱 | 布立尼布 |
CAS號(hào) | 649735-46-6 |
分子式 | C19H19FN4O3 |
分子量 | 370.38 |
外觀 | White to light brown powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Brivanib | BMS-540215 |
---|---|
中文名稱 | 布立尼布 |
CAS號(hào) | 649735-46-6 |
分子式 | C19H19FN4O3 |
分子量 | 370.38 |
外觀 | White to light brown powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with an IC50 of 25 nM, and has moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β.
PMID: 16570908 DOI: 10.1021/jm051106d
PMID: 26528545 PMCID: PMC4631495 DOI: 10.1371/journal.pone.0142355