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特司林

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Tesirine | SG3249

產(chǎn)品編號(hào):CL2658 CAS No.:1595275-62-9 MDLNo: 分子式:C75H101N9O23 分子量:1496.65
規(guī)格 庫(kù)存 目錄價(jià) 會(huì)員專(zhuān)享價(jià) 數(shù)量
1 mg 3-5days ¥21660.00 登錄后可見(jiàn)
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5 mg 3-5days ¥46360.00 登錄后可見(jiàn)
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基本信息
英文名稱(chēng) Tesirine | SG3249
中文名稱(chēng)特司林
CAS號(hào)1595275-62-9
分子式C75H101N9O23
分子量1496.65
外觀 White to light yellow powder
儲(chǔ)存條件Avoid light, nitrogen, -20 ℃
產(chǎn)品詳情

Tesirine (SG-3249; SG3249), cathepsin B-cleavable valine-alanine pyrrolobenzodiazepine (PBD) dimer used as an antibody-drug conjugate (ADC) payload; Tesirine was designed to combine the potent antitumor activity with desirable physicochemical properties such as favorable hydrophobicity and improved conjugation characteristics. Rovalpituzumab tesirine is a first-in-class ADC directed against delta-like protein 3 (DLL3), a novel target identified in tumour-initiating cells and expressed in small-cell lung cancer.

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