英文名稱 | Sulfo-PDBA-DM4 |
---|---|
中文名稱 | Sulfo-PDBA-DM4 |
CAS號 | 1461704-01-7 |
分子式 | C42H60ClN3O15S3 |
分子量 | 978.58 |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Sulfo-PDBA-DM4 |
---|---|
中文名稱 | Sulfo-PDBA-DM4 |
CAS號 | 1461704-01-7 |
分子式 | C42H60ClN3O15S3 |
分子量 | 978.58 |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Sulfo-PDBA-DM4 is a drug-linker conjugate for antibody-drug conjugate (ADC) applications, combining the potent tubulin inhibitor DM4 with the gluthatione-cleavable linker Sulfo-PDBA. This configuration harnesses DM4's cytotoxic potential through Sulfo-PDBA's targeted delivery mechanism.