英文名稱 | BL-918 |
---|---|
中文名稱 | BL-918 |
CAS號 | 2101517-69-3 |
分子式 | C23H15F8N3OS |
分子量 | 533.44 |
外觀 | White to off-white powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
英文名稱 | BL-918 |
---|---|
中文名稱 | BL-918 |
CAS號 | 2101517-69-3 |
分子式 | C23H15F8N3OS |
分子量 | 533.44 |
外觀 | White to off-white powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
BL-918 is an orally active UNC-51-like kinase 1 (ULK1) activator with an EC50 of 24.14 nM. BL-918 exerts its cytoprotective autophagic effect by targeting ULK complex. BL-918 has the potential for Parkinson’s disease (PD) treatment.
PMID: 29561612 DOI: 10.1021/acs.jmedchem.7b01575