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規(guī)格	庫存	目錄價	會員專享價	數(shù)量
1 g	In-stock	￥150.00	登錄后可見	- +
5 g	In-stock	￥450.00	登錄后可見	- +

規(guī)格

庫存

目錄價

會員專享價

數(shù)量

1 g

In-stock

￥150.00

登錄后可見

- +

5 g

In-stock

￥450.00

登錄后可見

- +

基本信息

英文名稱	(S)-(+)-Camptothecin \| CPT \| \| NSC-100880 \|
中文名稱	(S)-(+)-喜樹堿
CAS號	7689-03-4
分子式	C20H16N2O4
分子量	348.35
外觀	Light yellow to yellow powder
儲存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產(chǎn)品詳情

Camptothecin is a cytotoxic, quinoline alkaloid, discovered as the active principle of extracts from the Chinese tree C. acuminate, that inhibits the DNA enzyme topoisomerase I (Top1). It binds the Top1-DNA cleavage complex, inducing DNA-strand breaks. Camptothecin has strong anti-tumor activity against a wide range of experimental tumors and inhibits both DNA and RNA synthesis in mammalian cells. It displays cytotoxity in HT-29 cells with an IC50 value of 10 nM and induces DNA damage at concentrations as low as 51 nM in whole cells and 12 nM in isolated nuclei in in vitro assays.

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HL1007

(S)-(+)-喜樹堿

7689-03-4 98+% In-stock

￥150.00 1 g